Clinical evaluation of the T. pallidum haemagglutination test.

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Clinical value of the Treponema pallidum haemagglutination test.

In 1,129 patients attending the Department for Sexually Transmitted Diseases, the serum was examined by three screening tests (VDRL slide, RPCF, and TPHA) and twelve cases of syphilis (1 per cent. of patients attenting the clinic) were discovered. Six of these patients were considered to have latent syphilis (5 acquired, 1 congenital) and were detected only by the TPHA; all six cases were confi...

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Appraisal of the Treponema pallidum haemagglutination test.

Several attempts have been made to use haemagglutination reactions for the diagnosis of syphilis between 1932 and 1958. The first reliable method was developed by Rathlev (1965). Further results of investigations with this method have been reported by authors from Japan and from the Venereal Disease Research Laboratory in Atlanta, U.S.A. Rathlev prepared the reagents for the test in the Statens...

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Evaluation of the equivocal test results of Treponema pallidum haemagglutination assay.

Two hundred and eighty Rapid Plasma Reagin (RPR) positive sera with an emphasis on cases with negative and borderline positive Treponema pallidum haemagglutination assay (TPHA) results were selected. Modified TPHA (M-TPHA) and fluorescent treponemal antibody absorption (FTA-abs) tests were used for comparison. One hundred and twenty five samples were TPHA negative, of which 78 and 69 cases were...

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Treponema pallidum specific IgM haemagglutination test for serodiagnosis of syphilis.

The Treponema pallidum specific IgM haemagglutination (TP-IgM-HA) test uses erythrocytes sensitised with antiserum to human IgM to separate IgM from IgG in serum. Specific antitreponemal IgM captured in this way is detected by adding a second reagent comprising erythrocytes sensitised with T pallidum antigen. Eighty two serum samples from 82 patients with untreated syphilis, 521 samples from 73...

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Treponema pallidum haemagglutination test for syphilis. Evaluation of a modified micro-method.

Passive haemagglutination of erythrocytes sensitized with antigen is an extremely sensitive method for the detection of antibody. Its application to the serological diagnosis of syphilis was first reported by Rathlev (1965, 1967), using a haemagglutination technique for the detection of specific antitreponemal antibody in which formolized tanned sheep cells sensitized with ultrasonicated materi...

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ژورنال

عنوان ژورنال: Sexually Transmitted Infections

سال: 1971

ISSN: 1368-4973

DOI: 10.1136/sti.47.2.73